Short Interest Declines 25%

Sangamo Biosciences (SGMO) Short Interest Update

DATE                                   SHORT INTEREST

12/31/15                                8,382,214 (6.16 days to cover)

12/15/15                              11,153,021 

11/30/15                              11,483,202

11/13/15                              11,088,163                    
10/30/15                              11,668,561 

10/15/15                              12,821,197    

9/30/15                                12,619,596

9/15/15                                10,882,795

8/31/15                                10,150,146

8/14/15                                  9,488,474

7/31/15                                  9,207,150

7/15/15                                  9,205,202

6/30/15                                  9,387,951
6/15/15                                  9,393,825
5/29/15                                  8,938,987
5/15/15                                  8,668,559
4/30/15                                  8,198,983
4/15/15                                  8,050,307
3/31/15                                  8,285,803
3/13/15                                  8,441,291
2/27/15                                  8,939,000
2/13/15                                  9,268,065
1/30/15                                  9,082,814
1/15/15                                  9,387,913