http://www.nature.com/news/the-science-to-look-out-for-in-2016-1.19073
Cut-and-paste genes
Human trials will get under way for treatments that use DNA-editing technologies. Sangamo Biosciences in Richmond, California, will test the use of enzymes called zinc-finger nucleases to correct a gene defect that causes haemo-philia. Working with Biogen of Cambridge, Massachusetts, it will also start a trial to look at whether the technique can boost a functional form of haemo-globin in people with the blood disorder β-thalassaemia. Scientists and ethicists hope to
agree on broad safety and ethical guidelines for gene editing in humans in late 2016. And this year could see the birth of the first gene-edited monkeys that show symptoms of the human disorders they are designed to model.
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